Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs. Shin S, Kim TH, Jeong SW, Chung SE, Lee DY, Kim DH, et al. Three-dimensional (3D)-printed devices composed of hydrophilic cap and hydrophobic body for improving buoyancy and gastric retention of domperidone tablets. 2017 529(1-2):523–30.Ĭharoenying T, Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Akkaramongkolporn P, Opanasopit P. 3D printing of tablets using inkjet with UV photoinitiation. 2016 42:87–90.Ĭlark EA, Alexander MR, Irvine DJ, Roberts CJ, Wallace MJ, Sharpe S, et al. Fabrication of polymer micro needles for transdermal drug delivery system using DLP based projection stereo-lithography. 3D printed microneedle patches using stereolithography (SLA) for intradermal insulin delivery. 2019 14(5):465–79.Įconomidou SN, Pere CPP, Reid A, Uddin MJ, Windmill JFC, Lamprou DA, et al. Complex formulations, simple techniques: can 3D printing technology be the midas touch in pharmaceutical industry? Asian J Pharm Sci. Lamichhane S, Bashyal S, Keum T, Noh G, Seo JE, Bastola R, et al. Fused-filament 3D printing (3DP) for fabrication of tablets. Goyanes A, Buanz AB, Basit AW, Gaisford S. Fused deposition modeling (FDM) 3D printed tablets for intragastric floating delivery of domperidone. Development of modified release 3D printed tablets (printlets) with pharmaceutical excipients using additive manufacturing. Goyanes A, Fina F, Martorana A, Sedough D, Gaisford S, Basit AW. In conclusion, the optimization of CPD for GRDDS using the experimental design provided the devices with desirable floating time and ideal drug release characteristics. The release kinetics of the drug from the devices fitted well with zero-order kinetics. Appropriate total floating time (TFT) of the devices (more than 3 h) was obtained with the device’s body, cap, and bottom thickness of 1.2, 1.8, and 2.9 mm, respectively. The in vitro floating time and drug release were evaluated using a USP dissolution apparatus II. The morphology of the CPD was observed using a digital microscope and scanning electron microscope (SEM). The central composite design was employed for the optimization of the devices. The CPD was fabricated using a fused deposition modeling (FDM) 3D printer.
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All 3D components can be conveniently accessed for free via SolidWorks’ 3D ContentCentral service.This study aimed to optimize the size of capsule-shaped 3D-printed devices (CPD) using an experimental design by the response surface methodology to provide a gastroretentive drug delivery system (GRDDS) with optimal floating time. are among those featured on 3D ContentCentral. of America, Misumi USA, Inc., CarrLane, Omron, and Bimba Manufacturing Co. Components from global suppliers such as SMC Corp. The 3D-enabled catalogs available on 3D ContentCentral showcase everything from sensors to large motors. 3D catalogs save product designers valuable design time they would otherwise spend searching through paper catalogs or talking on the phone with the supplier’s sales support staff to find and configure a supplier component. They can then check precise form and fit by downloading the model or drawing directly into their designs, ensuring the parts they’re buying work with their design. * improved content upload tools that let engineers upload content by simply dragging and dropping.Įngineers can streamline product development with 3D ContentCentral by finding and configuring the part they need from online catalogs in seconds, not weeks. * personalization features, such as “M圓DCC” enable users to create their own area of the site to help focus on their particular needs and * community features, including content search, user ratings, and tools to request content from the community all give engineers more information about content creators
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* support for more content types, including parts/assemblies for almost all CAD tools, as well as 2D blocks, SolidWorks® software macros, and library features Key enhancements in 3D ContentCentral 2008 include:
#3d content central 3d update#
SolidWorks Corporation unveils the 3D ContentCentral® 2008 software service, the latest update of its online community that allows engineers to download and share content globally.ģD ContentCentral is free to registered engineers and designers who use it to share design information across geographies, sharing 3D models and 2D drawings with other design teams, regardless of their CAD system.
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